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In addition to self-reported smoking status and CO measures taken at each visit, urinary anabasine and anatabine concentration will be used as the principle objective measure of the primary outcome (continuous abstinence from smoking during the last 4 weeks of treatment)

[186] A study conducted by Scripps Institution of Oceanography showed that the average plastic content in the stomachs of 141 mesopelagic fish over 27 different species was 9.2%

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